Comparison of Ocular Surface Changes Following Laser-Assisted in Situ Keratomileusis and Photorefractive Keratectomy: Cross-Sectional Study

Objective: To compare the ocular surface changes following Femtosecond laser in situ keratomileusis (Femto-LASIK) and photorefractive keratectomy (PRK). Material Methods: TThis prospective study included 74 eyes of 37 patients: 34 were Femto-LASIK group, 40 PRK group. Schirmer test, tear break-up time, conjunctival impression cytology (CIC) used to determine before 1 month, 3 months after or Femto-LASIK. Results: There no significant differences between LASIK group mean CIC scores first month (p > .05, for each). However, a difference observed at goblet cell density (GCD) third =0.008). Comparing showed improvements GCD epithelial sheet =0.005, p =0.001, respectively). occurred FemtoLASIK Conclusion: We histopathological perilimbal conjunctiva groups surgery. It was that these continued 3rd postoperative month. Although improved significantly it still lower than preoperatively. can say play primary role pathogenesis dry eye even cause more severe course DED patients.